Article
Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes.
The Journal of clinical endocrinology and metabolism - 1 Apr 2004
Möhlig Matthias, Boeing Heiner, Spranger Joachim, Osterhoff Martin, Kroke Anja, Fisher Eva, Bergmann Manuela M, Ristow Michael, Hoffmann Kurt, Pfeiffer Andreas F H
Abstract excerpt
Increased levels of IL-6 add further risk to the impact of obesity in respect to the development of type 2 diabetes mellitus (T2DM). A C-174G polymorphism within the IL-6 promoter region was shown to influence transcription rate of IL-6. We made use of a nested case-control study within the Europ...
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