Article
HER2 polymorphism and breast cancer risk in Portugal.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jun 2004
Pinto D, Vasconcelos A, Costa S, Pereira D, Rodrigues H, Lopes C, Medeiros R
Abstract excerpt
Breast cancer is a major public health problem around the world, and its carcinogenesis is not yet well understood. The human epidermal growth factor Receptor 2 (HER2) seems to play an important role in the development of this neoplasia, and genetic alterations in this gene, such as point mutations and polymorphisms have been detected in breast cancer patients. We analysed the frequency of a single nucleotide...
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