Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The lymphocyte HIV reservoir in patients on long-term HAART is a memory of virus evolution.

AIDS (London, England) - 21 May 2004

Lambotte Olivier, Chaix Marie-Laure, Gubler Brigitte, Nasreddine Nadine, Wallon Christine, Goujard Cécile, Rouzioux Christine, Taoufik Yassine, Delfraissy Jean-François

Abstract excerpt

OBJECTIVE: To investigate the dynamics of the lymphocyte HIV reservoir in patients on prolonged and effective highly active antiretroviral therapy (HAART). DESIGN: Nine HAART-treated patients were selected on the basis of long-term infection and long-term undetectable plasma viral RNA. Five patients had received antiretroviral therapy before HAART. We compared a polymorphic region of the env gene (C2V4), and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiretroviral Therapy, Highly Active
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chronic Disease

Share to Disease Reservoirs

Share to Drug Resistance, Viral

Share to Genes, env

Share to Genes, pol

Share to Sequence Analysis, RNA

Source

Identifiers

PMID: 15166530
DOI: 10.1097/00002030-200405210-00008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The lymphocyte HIV reservoir in patients on long-term HAART is a memory of virus evolution.PMID 15166530Read ↗

A long-term latent reservoir for HIV-1: discovery and clinical implicationsSemantic proximity Read ↗

HIV-1 diversity in viral reservoirs obtained from circulating T-cell subsets during early ART and beyond.Semantic proximity Read ↗

The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over timeSemantic proximity Read ↗

The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time.Semantic proximity Read ↗

HIV-1 variants are archived throughout infection and persist in the reservoir.Semantic proximity Read ↗

Establishment and stability of the latent HIV-1 DNA reservoir.Semantic proximity Read ↗

Evolution of Envelope Sequences of Human Immunodeficiency Virus Type 1 in Cellular Reservoirs in the Setting of Potent Antiviral TherapySemantic proximity Read ↗

Genetic Diversity, Compartmentalization, and Age of HIV Proviruses Persisting in CD4+ T Cell Subsets during Long-Term Combination Antiretroviral Therapy.Semantic proximity Read ↗

Proviral Turnover During Untreated HIV Infection Is Dynamic and Variable Between Hosts, Impacting Reservoir Composition on ARTSemantic proximity Read ↗

Low-level plasma HIVs in patients on prolonged suppressive highly active antiretroviral therapy are produced mostly by cells other than CD4 T-cells.Semantic proximity Read ↗

In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV ControlSemantic proximity Read ↗

The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.