Article
Mapping complex disease loci in whole-genome association studies.
Nature - 27 May 2004
Carlson Christopher S, Eberle Michael A, Kruglyak Leonid, Nickerson Deborah A
Abstract excerpt
Identification of the genetic polymorphisms that contribute to susceptibility for common diseases such as type 2 diabetes and schizophrenia will aid in the development of diagnostics and therapeutics. Previous studies have focused on the technique of genetic linkage, but new technologies and experimental resources make whole-genome association studies more feasible. Association studies of this type have good...
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