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Article

Mapping rare and common causal alleles for complex human diseases.

Cell - 30 Sept 2011

Raychaudhuri Soumya

Abstract excerpt

Advances in genotyping and sequencing technologies have revolutionized the genetics of complex disease by locating rare and common variants that influence an individual's risk for diseases, such as diabetes, cancers, and psychiatric disorders. However, to capitalize on these data for prevention and therapies requires the identification of causal alleles and a mechanistic understanding for how these variants...

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Identifiers

PMID: 21962507
DOI: 10.1016/j.cell.2011.09.011
PMCID: PMC3198013

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