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Article

Impaired plasmacytoid dendritic cell maturation and differential chemotaxis in chronic hepatitis C virus: associations with antiviral treatment outcomes.

Gut - 1 Jul 2009

Mengshol J A, Golden-Mason L, Castelblanco N, Im K A, Dillon S M, Wilson C C, Rosen H R

Abstract excerpt

BACKGROUND: Dendritic cell (DC) defects may contribute to chronicity in hepatitis C virus (HCV) infection and determine response to PEG-interferon and ribavirin therapy via poor T cell stimulation. Studies to date have produced inconsistent results regarding DC maturation and function: no large study has examined DCs before and after therapy. AIMS: We examined if DC defects in maturation and chemotaxis are...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Hepatitis C, Chronic

Share to Receptors, Chemokine

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Source

Open in PubMed Open full text

Identifiers

PMID: 19193669
DOI: 10.1136/gut.2008.168948
PMCID: PMC2689392

Genes

CCR7
CXCL10
CXCL12
CXCR3
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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