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Article

Differential expression of menin in sporadic pituitary adenomas.

1 Jun 2004

Abstract excerpt

Pituitary adenomas represent one of the key features of multiple endocrine neoplasia type 1. The gene involved in this syndrome (MEN1) is a putative tumor suppressor, that codes for a 610-amino acid nuclear protein termed 'menin'. Analyses of sporadic pituitary adenomas have so far failed to reveal MEN1 mutations or defects in MEN1 transcription in these tumors. In the present study we detected menin protein...

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PMID: 15163308
DOI: 10.1677/erc.0.0110333

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