High-Resolution Array-Based Comparative Genomic Hybridization for Distinguishing Paraffin-Embedded Spitz Nevi and Melanomas

Abstract excerpt

Distinguishing between Spitz nevus and melanoma presents a challenging task for clinicians and pathologists. Most of these lesions are submitted entirely in formalin for histologic analysis by conventional hematoxylin and eosin-stained sections, and fresh-frozen material for ancillary studies is rarely collected. Molecular techniques, such as comparative genomic hybridization (CGH), can detect chromosomal...

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