Article
N-acetyltransferase (NAT2) polymorphism and breast cancer susceptibility: a lack of association in a case-control study of Turkish population.
International journal of toxicology - 1 Jan 2000
Kocabaş Neslihan Aygün, Sardaş Semra, Cholerton Suzanne, Daly Ann K, Karakaya Ali Esat
Abstract excerpt
Increased exposure to environmental carcinogens, including several aromatic and heterocyclic amines (HAs), is suspected to be one factor contributing to incidence of breast cancer. The N-acetyltransferase 2 (NAT2) acetylation polymorphism have been associated with a number of drug-induced toxicities and cancer in various tissues, resulting from decreased capacity to activate/deactivate several aromatic amine,...
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