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Article

The nucleolus is involved in mRNA export from the nucleus in fission yeast.

Journal of cell science - 15 Jun 2004

Ideue Takashi, Azad Abul Kalam, Yoshida Jun-ichi, Matsusaka Tadao, Yanagida Mitsuhiro, Ohshima Yasumi, Tani Tokio

Abstract excerpt

To elucidate the mechanism of mRNA export from the nucleus, we isolated five novel temperature-sensitive mutants (ptr7 to ptr11) that accumulate poly(A)(+) RNA in the nuclei at the nonpermissive temperature in Schizosaccharomyces pombe. Of those, the ptr11 mutation was found in the top2(+) gene encoding DNA topoisomerase II. In addition to the nuclear accumulation of poly(A)(+) RNA, ptr11 exhibited the cut (cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15161942
DOI: 10.1242/jcs.01155

Genes

TBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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