Article
Differential regulation of gene expression following CD40 activation of leukemic compared to healthy B cells.
Blood - 15 Dec 2004
Gricks Clair S, Zahrieh David, Zauls A Jason, Gorgun Gullu, Drandi Daniela, Mauerer Katja, Neuberg Donna, Gribben John G
Abstract excerpt
It is possible to differentiate malignant from healthy cells and to classify diseases based on identification of specific gene expression profiles. We hypothesized that gene expression profiling could also be used to identify differential activation of healthy and malignant cells, and as a model for this, we examined the molecular sequelae of CD40 activation of healthy and B-cell chronic lymphocytic leukemia...
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