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Article

Basic fibroblast growth factor inhibits radiation-induced apoptosis of HUVECs. II. The RAS/MAPK pathway and phosphorylation of BAD at serine 112.

Radiation research - 1 Jun 2004

Gu Qingyang, Wang Dewen, Wang Xiaodan, Peng Ruiyun, Liu Jie, Deng Hua, Wang Zhaohai, Jiang Tao

Abstract excerpt

Radiation-induced endothelial cell apoptosis is involved in the development of many radiation injuries, including radiation-induced skin ulcers. The proangiogenic growth factor basic fibroblast growth factor (bFGF, NUDT6) enhances endothelial cell survival. In the present study, we set up a model of apoptosis in which primary cultured human umbilical vein endothelial cells (HUVECs) were irradiated with (60)Co...

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Source

Identifiers

PMID: 15161349
DOI: 10.1667/rr3159

Genes

BAD
NUDT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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