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Article

Electrochemical detection of DNA triplet repeat expansion.

Journal of the American Chemical Society - 2 Jun 2004

Fojta Miroslav, Havran Ludek, Vojtiskova Marie, Palecek Emil

Abstract excerpt

Hereditary neurodegenerative diseases are connected with the expansion of trinucleotide repetitive sequences in genomic DNA. Molecular diagnosis of these diseases is based on the determination of the triplet repeat length. Currently used methods involve PCR amplification followed by electrophoretic determination of the amplicon size. We propose a novel electrochemical technique based on hybridization of target...

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PMID: 15161263
DOI: 10.1021/ja048781h

Genes

GAA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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