Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation.

Life sciences - 15 May 2021

Zhang Sunyun, Luo Qiong, Feng Rui, Yang Fan, Xu Qian, Chen Xiangqi, Yang Sheng

Abstract excerpt

AIMS: ADP ribosylation factor guanylate kinase 1 (ASAP1), a phospholipid-dependent guanosine triphosphate (GTP)ase activating protein, has been reported to be involved in the development of various malignant tumors. However, the biological function of ASAP1 in gastric cancer (GC) remains unclear. This study was to investigate its effect and the underlying mechanism for the malignant phenotype of GC. MATERIALS AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Apoptosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Focal Adhesion Kinase 1

Share to Gene Expression Regulation, Neoplastic

Share to Guanylate Kinases

Share to Phosphorylation

Share to Stomach Neoplasms

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 33639150
DOI: 10.1016/j.lfs.2021.119264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation.PMID 33639150Read ↗

Role of ADP Ribosylation Factor Guanylate Kinase 1 in the Malignant Biological Behavior of Gastric CancerSemantic proximity Read ↗

ASAP1 promotes tumor progression and angiogenesis and independently predicts poor prognosis and lymph node metastasis of gastric cancerSemantic proximity Read ↗

Increased lncRNA AFAP1-AS1 expression predicts poor prognosis and promotes malignant phenotypes in gastric cancer.Semantic proximity Read ↗

AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathwaySemantic proximity Read ↗

ITGA5 Promotes Tumor Progression through the Activation of the FAK/AKT Signaling Pathway in Human Gastric CancerSemantic proximity Read ↗

Adhesion G protein-coupled receptor G2 accelerates the proliferation of cancer cells by promoting the formation of CDK4/CCND1Semantic proximity Read ↗

Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.Semantic proximity Read ↗

RKIP inhibits the malignant phenotypes of gastric cancer cells.Semantic proximity Read ↗

Cross-Talk of Focal Adhesion-Related Gene Defines Prognosis and the Immune Microenvironment in Gastric CancerSemantic proximity Read ↗

ATP5B promotes the metastasis and growth of gastric cancer by activating the FAK/AKT/MMP2 pathwaySemantic proximity Read ↗

Development of Combination Strategies for Focal Adhesion Kinase Inhibition in Diffuse Gastric CancerSemantic proximity Read ↗

Growth arrest‐specific gene 1 is downregulated and inhibits tumor growth in gastric cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.