Article
Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3.
Biochemical and biophysical research communications - 18 Jun 2004
Court Naomi W, Kuo Ivana, Quigley Oonagh, Bogoyevitch Marie A
Abstract excerpt
Mitogen-activated protein kinases (MAPKs) transduce extracellular signals into responses such as growth, differentiation, and death through their phosphorylation of specific substrate proteins. Early studies showed the consensus sequence (Pro/X)-X-(Ser/Thr)-Pro to be phosphorylated by MAPKs. Docking domains such as the "kinase interaction motif" (KIM) also appear to be crucial for efficient substrate...
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