Article
Translational control of apolipoprotein B mRNA: regulation via cis elements in the 5' and 3' untranslated regions.
Biochemistry - 1 Jun 2004
Pontrelli Louisa, Sidiropoulos Konstantinos Gus, Adeli Khosrow
Abstract excerpt
Translational control of apolipoprotein B (apoB) mRNA has been previously documented; however, the molecular mechanisms that govern translation of apoB mRNA are unknown. We investigated the role of the untranslated regions (UTR) in the regulation of apoB mRNA translation first by analyzing apoB UTR sequences using M-fold, a program used to predict RNA secondary structure. M-fold analysis revealed hairpin-like...
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