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Article

Caspase-3 and caspase-9 mediate developmental apoptosis in the mouse olfactory system.

The Journal of comparative neurology - 14 Jun 2004

Cowan Catherine M, Roskams A Jane

Abstract excerpt

Neuronal apoptosis is a key component in the sculpting of tissues during embryonic and postnatal development and is driven largely by the action of caspases. In the mouse olfactory system, caspase-3 and -9 are expressed in olfactory receptor neurons (ORNs) of adult mice, and their selective retrograde activation drives ORN apoptosis following ablation of their target, the olfactory bulb (OB). Here, we show that...

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Identifiers

PMID: 15156583
DOI: 10.1002/cne.20120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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