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Article

The role of the effector caspases drICE and dcp-1 for cell death and corpse clearance in the developing optic lobe in Drosophila.

Developmental biology - 15 Aug 2015

Akagawa Hiromi, Hara Yusuke, Togane Yu, Iwabuchi Kikuo, Hiraoka Tsuyoshi, Tsujimura Hidenobu

Abstract excerpt

In the developing Drosophila optic lobe, cell death occurs via apoptosis and in a distinctive spatio-temporal pattern of dying cell clusters. We analyzed the role of effector caspases drICE and dcp-1 in optic lobe cell death and subsequent corpse clearance using mutants. Neurons in many clusters required either drICE or dcp-1 and each one is sufficient. This suggests that drICE and dcp-1 function in cell death...

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Identifiers

PMID: 26022392
DOI: 10.1016/j.ydbio.2015.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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