Genetics of human left-right axis malformations.

Abstract excerpt

Like all vertebrates, humans establish anatomic left-right asymmetry during embryogenesis. Variation from this normal arrangement (situs solitus) results in heterotaxy, expressed either as randomization (situs ambiguus) or complete reversal (situs inversus) of normal organ position. Familial heterotaxy occurs with autosomal dominant, recessive, and X-linked inheritance. All possible situs variants--solitus,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Body Patterning
• Share to Congenital Abnormalities
• Share to Forecasting