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Article

Differential gene expression in a Bacteroides fragilis metronidazole-resistant mutant.

The Journal of antimicrobial chemotherapy - 1 Jul 2004

Diniz Claudio Galuppo, Farias Luiz M, Carvalho Maria Auxiliadora R, Rocha Edson R, Smith C Jeffrey

Abstract excerpt

OBJECTIVES: The current work focused on molecular changes in a spontaneous Bacteroides fragilismutant selected by low concentrations of metronidazole as an adaptive response to the drug. METHODS: A metronidazole-resistant strain derived from B. fragilis ATCC 25285 was selected by passage in the presence of drug using 0-4 mg/L gradient plates. Using a combination of proteomics for identification of differentially...

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Share to Bacteroides fragilis
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoresis, Gel, Two-Dimensional

Share to Fermentation

Share to Gene Expression Regulation, Bacterial

Share to Metronidazole

Share to Mutagenesis, Insertional

Source

Identifiers

PMID: 15150173
DOI: 10.1093/jac/dkh256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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