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Article

BRCA1 mutations in South African breast and/or ovarian cancer families: evidence of a novel founder mutation in Afrikaner families.

International journal of cancer - 10 Jul 2004

Reeves Michelle D, Yawitch Tali M, van der Merwe Nerina C, van den Berg Hester J, Dreyer Greta, van Rensburg Elizabeth J

Abstract excerpt

Germ-line mutations within BRCA1 are responsible for different proportions of inherited susceptibility to breast/ovarian cancer, and the spectrum of mutations within this gene is often unique to certain populations. At this time, there have been no reports regarding the role of BRCA1 in South African breast and/or ovarian cancer families. We therefore screened 90 South African breast/ovarian cancer families for...

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Source

Identifiers

PMID: 15146556
DOI: 10.1002/ijc.20186

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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