Article
BRCA1 mutations in Algerian breast cancer patients: high frequency in young, sporadic cases.
International journal of medical sciences - 8 Jul 2008
Uhrhammer Nancy, Abdelouahab Amina, Lafarge Laurence, Feillel Viviane, Ben Dib Ahmed, Bignon Yves-Jean
Abstract excerpt
Breast cancer rates and median age of onset differ between Western Europe and North Africa. In Western populations, 5 to 10 % of breast cancer cases can be attributed to major genetic factors such as BRCA1 and BRCA2, while this attribution is not yet well defined among Africans. To help determine the contribution of BRCA1 mutations to breast cancer in a North African population, we analysed genomic DNA from...
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