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Article

Characterization of salvicine-resistant lung adenocarcinoma A549/SAL cell line.

International journal of cancer - 10 Jul 2004

Miao Ze-Hong, Tong Lin-Jiang, Zhang Jin-Sheng, Han Jia-Xian, Ding Jian

Abstract excerpt

Salvicine is a diterpenoid quinone derived from a traditional Chinese medication that has been shown to possess potent in vitro and in vivo antitumor effects. This compound, which inhibits the activity of Topoisomerase II, was found to equipotently kill various multidrug-resistant tumor cells and their corresponding parental counterparts in vitro and to inhibit mdr1/P-gp expression in multidrug-resistant K562/A02...

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PMID: 15146550
DOI: 10.1002/ijc.20026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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