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Article

Targeting the invasive phenotype of cisplatin-resistant non-small cell lung cancer cells by a novel histone deacetylase inhibitor.

Biochemical pharmacology - 15 Mar 2015

Zuco Valentina, Cassinelli Giuliana, Cossa Giacomo, Gatti Laura, Favini Enrica, Tortoreto Monica, Cominetti Denis, Scanziani Eugenio, Castiglioni Vittoria, Cincinelli Raffaella, Giannini Giuseppe, Zunino Franco, Zaffaroni Nadia, Lanzi Cinzia, Perego Paola

Abstract excerpt

Non-Small Cell Lung Cancer (NSCLC) remains an aggressive and fatal disease with low responsiveness to chemotherapy, frequent drug resistance development and metastatic behavior. Platinum-based therapy is the standard of care for NSCLC with limited benefits. Since epigenetic alterations have been implicated in the aggressive behavior of lung cancer, the purpose of the present study was to examine the capability of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25600908
DOI: 10.1016/j.bcp.2015.01.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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