Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regeneration of Male Germline Stem Cells by Spermatogonial Dedifferentiation in Vivo

18 May 2004

Abstract excerpt

Although the ability of engrafted stem cells to regenerate tissue has received much attention, the molecular mechanisms controlling regeneration are poorly understood. In the Drosophila male germline, local activation of the Janus kinase-signal transducer and activator of transcription (Jak-STAT) pathway maintains stem cells; germline stem cells lacking Jak-STAT signaling differentiate into spermatogonia without...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Developmental Biology and Gene Regulation
Share to Reproductive biology and impacts on aquatic species
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15143218
DOI: 10.1126/science.1097676

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regeneration of Male Germline Stem Cells by Spermatogonial Dedifferentiation in VivoPMID 15143218Read ↗

Spermatogonial stem cells: A story of self-renewal and differentiationSemantic proximity Read ↗

Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling.Semantic proximity Read ↗

Niche-dependent modular regulation of the stem cell transcriptome separates cell identity and potentialSemantic proximity Read ↗

Spermatogonial stem cell regulation and spermatogenesisSemantic proximity Read ↗

Germline stem cells: toward the regeneration of spermatogenesisSemantic proximity Read ↗

Regulation of Mouse Spermatogonial Stem Cell Differentiation by STAT3 Signaling1Semantic proximity Read ↗

Molecular regulation of spermatogonial stem cell renewal and differentiationSemantic proximity Read ↗

THE TAO OF STEM CELLS IN THE GERMLINESemantic proximity Read ↗

Maintaining the male germline: regulation of spermatogonial stem cellsSemantic proximity Read ↗

Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue.Semantic proximity Read ↗

Mouse differentiating spermatogonia can generate germinal stem cells in vivoSemantic proximity Read ↗

Dedifferentiating Spermatogonia Outcompete Somatic Stem Cells for Niche Occupancy in the Drosophila TestisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.