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Article

Profiling of internalizing tumor-associated antigens on breast and pancreatic cancer cells by reversed genomics.

Cancer letters - 28 May 2004

Fransson Johan, Ek Sara, Ellmark Peter, Söderlind Eskil, Borrebaeck Carl A K, Furebring Christina

Abstract excerpt

Human antibodies directed towards functionally associated tumor antigens have great potentials as adjuvant treatment in cancer therapy. Here we describe an efficient subtractive approach to select single chain Fv (scFv) antibodies, specifically binding to unknown rapidly internalizing tumor-associated antigens (TAA) on human breast and pancreatic carcinoma cell lines. After re-engineering the scFv into intact IgG...

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Identifiers

PMID: 15142683
DOI: 10.1016/j.canlet.2003.11.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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