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Article

Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies.

Molecular immunology - 1 Jul 2007

Goenaga Anne-Laure, Zhou Yu, Legay Christine, Bougherara Houcine, Huang Lan, Liu Bin, Drummond Daryl C, Kirpotin Dmitri B, Auclair Christian, Marks James D, Poul Marie-Alix

Abstract excerpt

To generate a panel of antibodies binding human breast cancers, a human single chain Fv phage display library was selected for rapid internalization into the SK-BR-3 breast cancer cell line. Thirteen unique antibodies were identified within the 55 cell binding antibodies studied, all of them showing specific staining of tumor cells compare to normal epithelial cells. Two of the antibodies bound the ErbB2 oncogene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17498801
DOI: 10.1016/j.molimm.2007.03.023
PMCID: PMC2739904

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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