Article
Discovery of putative breast cancer antigens using an integrative platform of genomics-driven immunoproteomics.
Proteomics - 1 Aug 2017
Qendro Veneta, Lundgren Deborah H, Palczewski Samuel, Hegde Poornima, Stevenson Christina, Perpetua Laurie, Latifi Ardian, Merriman Jesse, Bugos Grace, Han David K
Abstract excerpt
Recent advances in cancer immuno-therapeutics such as checkpoint inhibitors, chimeric antigen-receptor T cells, and tumor infiltrating T cells (TIL) are now significantly impacting cancer patients in a positive manner. Although very promising, reports indicate no more than 25% of cases result in complete remission. One of the limitations of these treatments is the identity of putative cancer antigens in each...
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