Article
Triple negative breast cancer: outcome correlation with immunohistochemical detection of basal markers.
The American journal of surgical pathology - 1 Jul 2010
Thike Aye Aye, Iqbal Jabed, Cheok Poh Yian, Chong Angela Phek Yoon, Tse Gary Man-Kit, Tan Benita, Tan Patrick, Wong Nan Soon, Tan Puay Hoon
Abstract excerpt
We earlier evaluated the relationship of 653 triple negative breast cancers (TNBC) with basal immunophenotypic expression by using antibodies to basal cytokeratins (CK5/6, CK14, CK17, 34betaE12), p63, smooth muscle actin (SMA), epidermal growth factor receptor, and CD117, and found that a triple panel of CK14, 34betaE12 and epidermal growth factor receptor determined 84% of our cases to be basal-like. Women with...
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