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Analysis of heart valve development in larval zebrafish

14 May 2009

Abstract excerpt

Malformations of the cardiac endocardial cushions (ECs) and valves are common congenital dysmorphisms in newborn infants. Many regulators of EC development have been identified, but the process of valve maturation is less well understood. Zebrafish have been used to understand cardiogenesis through 6 days postfertilization, yet mature heart valves are not present at this stage. By analyzing valve development in...

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PMID: 19449301
DOI: 10.1002/dvdy.21976

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