Molecular mechanisms of end-organ resistance.

doi:10.1016/j.ghir.2004.03.012

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Article

Molecular mechanisms of end-organ resistance.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Jun 2004

Jameson J Larry

Abstract excerpt

Hormone resistance is caused by mutations in hormone receptors or by functional desensitization of hormone signaling pathways. Mutations that cause hormone resistance have been described for most classes of hormones, including peptides like growth-hormone releasing hormone (GHRH); large proteins such as insulin and the glycoprotein hormones; steroid hormones; and even ions such as calcium. In the case of...

Topics

Animals
Hormones
Humans
Insulin Resistance
Mutation
Receptors, Cell Surface
Receptors, Cytoplasmic and Nuclear
Signal Transduction
Syndrome

Source

Open in PubMed

Identifiers

PMID: 15135777
DOI: 10.1016/j.ghir.2004.03.012

Genes

GHRH
AMH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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