Article
Activating and inactivating hormone receptor mutations.
Hormone research - 1 Jan 2000
Huhtaniemi I
Abstract excerpt
The unravelling of gene structures of hormones, their receptors and the various components of their signal transduction apparatus has enabled diagnosis of the aetiology of hormone resistance at the molecular level. Inactivating mutations can be found in hormone receptor genes or those encoding components of the post-receptor signal transduction cascade. Another category of receptor mutation is that causing...
Topics
- Animals
- Hormones
- Humans
- Mutation
- Receptors, Cell Surface