Germline mutational analysis of CDH1 and pathologic features in familial cancer syndrome with diffuse gastric cancer/breast cancer proband in a Chinese family.

doi:10.1016/j.ejso.2004.03.004

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Article

Germline mutational analysis of CDH1 and pathologic features in familial cancer syndrome with diffuse gastric cancer/breast cancer proband in a Chinese family.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Jun 2004

Zhu Z G, Yu Y Y, Zhang Y, Ji J, Zhang J, Liu B Y, Chen X H, Lu Y, Jiang H S, Bu L, Hu L D, Kong X Y

Abstract excerpt

AIMS: Hereditary non-polyposis colorectal cancer, thyroid medullary carcinoma, breast/ovarian cancer and gastric cancer/breast cancer syndrome are encountered in surgery. Some gastric cancer/breast cancer syndrome may be the result of a CDH1 germline mutation. This is the first report of CDH1 ger...

Topics

Adult
Amino Acid Substitution
Asian People
Base Sequence
Breast Neoplasms
Cadherins
Carbohydrate Dehydrogenases
Carcinoma, Ductal
China
Colorectal Neoplasms
Cytoskeletal Proteins
DNA, Neoplasm
Exons

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Genetic Predisposition to Disease

Germ-Line Mutation

Humans

Immunohistochemistry

Source

Open in PubMed

Identifiers

PMID: 15135482
DOI: 10.1016/j.ejso.2004.03.004

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15135482-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.