Article
Interleukin-10 production genotype protects against acute persistent rejection after lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 May 2004
Zheng Hong Xia, Burckart Gilbert J, McCurry Kenneth, Webber Steven, Ristich Julia, Iacono Aldo, Dauber James, McDade Kevin, Grgurich Wayne, Zaldonis Diana, Pillage Gina, Griffith Bartley P, Zeevi Adriana
Abstract excerpt
BACKGROUND: Our previous studies demonstrated that cytokine gene polymorphisms are related to acute rejection in pediatric heart transplantation; a decreased tumor necrosis factor (TNF)-alpha production genotype combined with an increased or intermediate interleukin (IL)-10 production genotype was associated with the smallest incidence of acute rejection. The objective of this study was to determine whether...
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