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Article

Circadian rhythms in behavior and clock gene expressions in the brain of mice lacking histidine decarboxylase.

Brain research. Molecular brain research - 19 May 2004

Abe Hiroshi, Honma Sato, Ohtsu Hiroshi, Honma Ken-Ichi

Abstract excerpt

To clarify functional roles of histamine in the circadian clock system, circadian rhythms of behavior and clock gene expression in the brain were examined in the mouse lacking histidine decarboxylase (HDC-/- mouse). Wheel-running and spontaneous locomotion were recorded under light-dark cycle (LD) and constant darkness (DD). mPer1, mPer2 and mBMAL1 mRNA expression rhythms under LD and DD were measured in the...

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Identifiers

PMID: 15135226
DOI: 10.1016/j.molbrainres.2004.02.015

Genes

HDC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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