Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of histaminergic neurons in development of epileptic seizures in EL mice.

Brain research. Molecular brain research - 6 Dec 2004

Yawata Izumi, Tanaka Kazuaki, Nakagawa Yukinori, Watanabe Yasuo, Murashima Yoshiya L, Nakano Kiwao

Abstract excerpt

The EL mouse is an animal model for hereditary temporal lobe epilepsy. When the mice receive weekly vestibular stimulation, e.g., 30 "tosses", 10-15 cm vertically, they start to convulse after 1-2 weeks. The aim of this study was to evaluate the role of the histaminergic neurons in the regulation of seizure development in the EL mice. The obtained results indicated that administration of either histidine, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Therapy, Combination
Share to Enzyme Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epilepsy

Share to Epilepsy, Temporal Lobe

Share to Histamine

Share to Histidine

Share to Mice, Neurologic Mutants

Share to Pyrimethamine

Source

Identifiers

PMID: 15548424
DOI: 10.1016/j.molbrainres.2004.08.019

Genes

HDC
HNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of histaminergic neurons in development of epileptic seizures in EL mice.PMID 15548424Read ↗

The histidine decarboxylase model of tic pathophysiology: a new focus on the histamine H3 receptorSemantic proximity Read ↗

Circadian rhythms in behavior and clock gene expressions in the brain of mice lacking histidine decarboxylase.Semantic proximity Read ↗

Anatomical, physiological, and pharmacological characteristics of histidine decarboxylase knock-out mice: evidence for the role of brain histamine in behavioral and sleep-wake control.Semantic proximity Read ↗

H1 histamine receptor densities are increased in brain regions of rats with genetically generalized epilepsies.Semantic proximity Read ↗

Histamine-HisCl1 receptor axis regulates wake-promoting signals in Drosophila melanogaster.Semantic proximity Read ↗

Mice lacking histidine decarboxylase exhibit abnormal mast cells.Semantic proximity Read ↗

Histidine Decarboxylase Knockout Mice as a Model of the Pathophysiology of Tourette Syndrome and Related Conditions.Semantic proximity Read ↗

Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice.Semantic proximity Read ↗

High-amplitude theta wave bursts characterizing narcoleptic mice and patients are also produced by histamine deficiency in mice.Semantic proximity Read ↗

Behavioural phenotype of histamine H4 receptor knockout mice: Focus on central neuronal functions.Semantic proximity Read ↗

Histaminergic modulation in Tourette syndromeSemantic proximity Read ↗

Behavioural characterization and amounts of brain monoamines and their metabolites in mice lacking histamine H1 receptors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.