Article
Oxygen free radical scavenger enzyme polymorphisms in systemic sclerosis.
Free radical biology & medicine - 1 Jun 2004
Tikly Mohammed, Marshall Sara E, Haldar Neil A, Gulumian Mary, Wordsworth Paul, Welsh Ken I
Abstract excerpt
We performed a case-control study of polymorphisms of glutathione S-transferase (GST) isoenzymes and manganese superoxide dismutase (MnSOD) in black South Africans with systemic sclerosis (SSc). The frequency of the GSTM1*B phenotype was significantly decreased in the overall SSc group compared with controls (OR=0.19, p(corr)<.05), implying a possible protective effect against development of the disease. There...
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