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Article

Molecular and functional analysis of Caenorhabditis elegans CHIP, a homologue of Mammalian CHIP.

FEBS letters - 7 May 2004

Khan Liakot A, Nukina Nobuyuki

Abstract excerpt

A recently identified molecule C-terminus of Hsc70 interacting protein (CHIP) has been reported to be an E3 ubiquitin ligase collaborating with molecular chaperones for the degradation of misfolded or unfolded proteins. The physiological roles of CHIP in animal and plant development remain largely unknown. Here, we show that the knockdown of CeCHIP by RNAi and knockout by a deletion mutation arrests the...

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Identifiers

PMID: 15135044
DOI: 10.1016/j.febslet.2004.03.084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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