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Article

Hepatitis C virus and the controversial role of the interferon sensitivity determining region in the response to interferon treatment.

Journal of medical virology - 1 Feb 2008

Torres-Puente Manuela, Cuevas José M, Jiménez-Hernández Nuria, Bracho María A, García-Robles Inmaculada, Carnicer Fernando, del Olmo Juan, Ortega Enrique, Moya Andrés, González-Candelas Fernando

Abstract excerpt

The degree of variability of the interferon sensitivity determining region (ISDR) in the hepatitis C virus (HCV) genome has been postulated to predict the response to interferon therapy, mainly in patients infected with subtype 1b, although this prediction has been the subject of a long controversy. This prediction has been tested by analyzing a cohort of 67 Spanish patients infected with HCV genotype 1, 23 of...

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PMID: 18098147
DOI: 10.1002/jmv.21060

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Hepatitis C virus and the controversial role of the interferon sensitivity determining region in the response to interferon treatment.PMID 18098147Read ↗

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