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Article

Molecular differences between sporadic serrated and conventional colorectal adenomas.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2004

Konishi Kazuo, Yamochi Toshiko, Makino Reiko, Kaneko Kazuhiro, Yamamoto Taikan, Nozawa Hisako, Katagiri Atsushi, Ito Hiroaki, Nakayama Kentarou, Ota Hidekazu, Mitamura Keiji, Imawari Michio

Abstract excerpt

PURPOSE: The purpose is to compare the molecular characteristics of serrated adenomas (SAs) with those of conventional adenomas (CADs) and hyperplastic polyps (HPs). EXPERIMENTAL DESIGN: We evaluated the proliferative activity and molecular alterations in 47 SAs (25 pure-type and 22 mixed-type), 71 CADs, and 23 HPs. RESULTS: The proliferative activity of SAs, as evaluated by Ki-67 expression, was intermediate...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Ki-67 Antigen

Share to MutL Protein Homolog 1

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 15131047
DOI: 10.1158/1078-0432.ccr-03-0334

Genes

KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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