[Colorectal serrated adenoma: diagnostic criteria and clinical implications].

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

[Colorectal serrated adenoma: diagnostic criteria and clinical implications].

Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 2007

Rüschoff J, Aust D, Hartmann A

Abstract excerpt

More than 40 years ago Morson (1962) coined the paradigm that adenomas are the main precursors of colorectal carcinoma (CRC) whereas hyperplastic polyps are "non-neoplastic" lesions without cancer risk. Later-on (1988) this was supported by Vogelstein's molecular adenoma-carcinoma progression model with APC mutations being a key-initiating molecular event (classic adenoma-carcinoma pathway). In 1992 a new...

Topics

Adenoma
Colonic Polyps
Colorectal Neoplasms
Diagnosis, Differential
Genes, APC
Humans
Hyperplasia
Mutation

Source

Open in PubMed

Identifiers

PMID: 18314605

Genes

APC
BRAF
MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics