Article
Molecular characteristics of serrated adenomas of the colorectum.
Gut - 1 Aug 2002
Sawyer E J, Cerar A, Hanby A M, Gorman P, Arends M, Talbot I C, Tomlinson I P M
Abstract excerpt
BACKGROUND: Serrated adenomas (SAs) of the colorectum combine architectural features of hyperplastic polyps and cytological features of classical adenomas. Molecular studies comparing SAs and classical adenomas suggest that each may be a distinct entity; in particular, it has been proposed that microsatellite instability (MSI) distinguishes SAs from classical adenomas and that SAs and the colorectal cancers...
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