Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA mutations and risk of prostate cancer in Ashkenazi Jews.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2004

Kirchhoff Tomas, Kauff Noah D, Mitra Nandita, Nafa Kedoudja, Huang Helen, Palmer Crystal, Gulati Tony, Wadsworth Eve, Donat Sheri, Robson Mark E, Ellis Nathan A, Offit Kenneth

Abstract excerpt

PURPOSE: The Breast Cancer Linkage Consortium and other family-based ascertainments have suggested that male carriers of BRCA mutations are at increased risk of prostate cancer. Several series looking at the frequency of BRCA mutations in unselected patients with prostate cancer have not confirmed this finding. To clarify this issue, we conducted a large case-control study. EXPERIMENTAL DESIGN: Blood specimens...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Logistic Models

Share to Odds Ratio

Share to Prostatic Neoplasms

Share to Risk Factors

Source

Identifiers

PMID: 15131025
DOI: 10.1158/1078-0432.ccr-03-0604

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA mutations and risk of prostate cancer in Ashkenazi Jews.PMID 15131025Read ↗

Germline BRCA mutations denote a clinicopathologic subset of prostate cancer.Semantic proximity Read ↗

Founder mutations in BRCA1/2 are not frequent in Canadian Ashkenazi Jewish men with prostate cancerSemantic proximity Read ↗

Common mutations in BRCA1 and BRCA2 do not contribute to early prostate cancer in Jewish men.Semantic proximity Read ↗

Associations of high-grade prostate cancer with BRCA1 and BRCA2 founder mutations.Semantic proximity Read ↗

BRCA1 and BRCA2 pathogenic variants and prostate cancer risk: systematic review and meta-analysis.Semantic proximity Read ↗

Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer.Semantic proximity Read ↗

The rate of the founder Jewish mutations in BRCA1 and BRCA2 in prostate cancer patients in Israel.Semantic proximity Read ↗

The role of BRCA1 and BRCA2 in prostate cancer.Semantic proximity Read ↗

A twofold increase in <i>BRCA</i> mutation related prostate cancer among Ashkenazi Israelis is not associated with distinctive histopathologySemantic proximity Read ↗

The role of the BRCA2 gene in susceptibility to prostate cancer revisited.Semantic proximity Read ↗

Decreased prostate cancer-specific survival of men with BRCA2 mutations from multiple breast cancer families.Semantic proximity Read ↗

Germline mutations in the BRCA2 gene and susceptibility to hereditary prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.