Article
Tumour necrosis factor (--308A) polymorphism in very preterm infants with bronchopulmonary dysplasia: a meta-analysis.
Archives of disease in childhood. Fetal and neonatal edition - 1 Jul 2009
Chauhan M, Bombell S, McGuire W
Abstract excerpt
BACKGROUND: Excessive release of tumour necrosis factor (TNF) may contribute to the pathogenesis of bronchopulmonary dysplasia (BPD) in very preterm infants. It has been proposed that the risk of developing BPD may be associated with host genetic factors that regulate TNF production. The most commonly studied variant is the guanine to adenine transition at position -308 nucleotides relative to the transcription...
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