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Knockout of two alanine racemase genes of Vibrio anguillarum and its potential as an attenuated vaccine in olive flounder (Paralichthys olivaceus)

2016-05-01

Abstract excerpt

Vibriosis caused by Vibrio anguillarum is one of the most common bacterial diseases in cultured fish worldwide. Alanine racemases (Alrs) catalyze conversion of l-alanine to d-alanine. As d-alanine is an essential component of the peptidoglycan layer of bacteria, the alanine racemase gene (alr) knockout bacteria cannot grow without d-alanine supplementation. In the genome of V. anguillarum, two alanine racemase gen...

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Literature Corpus work
6f22a910-432f-5407-a630-461139e89c05
DOI
10.1016/j.aquaculture.2016.02.019
Open publication

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