Article
CRM1-dependent, but not ARE-mediated, nuclear export of IFN-alpha1 mRNA.
Journal of cell science - 1 May 2004
Kimura Tominori, Hashimoto Iwao, Nagase Takahiro, Fujisawa Jun-Ichi
Abstract excerpt
While the bulk of cellular mRNA is known to be exported by the TAP pathway, export of specific subsets of cellular mRNAs may rely on chromosome region maintenance 1 (CRM1). One line of evidence supporting this hypothesis comes from the study of mRNAs of certain early response genes (ERGs) containing the adenylate uridylate-rich element (ARE) in their 3' untranslated regions (3' UTRs). It was reported that...
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