Article
Association of the mitochondrial DNA 16189 T to C variant with lacunar cerebral infarction: evidence from a hospital-based case-control study.
Annals of the New York Academy of Sciences - 1 Apr 2004
Liou Chia-Wei, Lin Tsu-Kung, Huang Feng-Mei, Chen Tzu-Ling, Lee Cheng-Feng, Chuang Yao-Chung, Tan Teng-Yeow, Chang Ku-Chou, Wei Yau-Huei
Abstract excerpt
A transition of T to C at nucleotide position 16189 in the hypervariable D-loop region of mitochondrial DNA (mtDNA) has attracted research interest for its probable correlation with increasing insulin resistance and development of diabetes mellitus (DM) in adult life. In this article, we present our observations of the positive relationship between this variant and cerebral infarction. Six hundred and one...
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