Article
The feasibility of neuropsychological endophenotypes in the search for genes associated with bipolar affective disorder.
Bipolar disorders - 1 Jun 2004
Glahn David C, Bearden Carrie E, Niendam Tara A, Escamilla Michael A
Abstract excerpt
OBJECTIVE: Efforts to identify genetic loci for bipolar disorder (BPD) have thus far proved elusive. The identification of processes mediating between genotype and phenotype (endophenotypes) may help resolve the carrier status of family members in genetic studies of polygenetic disorders with imperfect penetrance, such as BPD. We reviewed the literature to determine if neuropsychological measures could be used as...
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