Article
Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD?
Journal of child psychology and psychiatry, and allied disciplines - 1 Jul 2005
Doyle Alysa E, Faraone Stephen V, Seidman Larry J, Willcutt Erik G, Nigg Joel T, Waldman Irwin D, Pennington Bruce F, Peart Joanne, Biederman Joseph
Abstract excerpt
BACKGROUND: Behavioral genetic studies provide strong evidence that attention-deficit/hyperactivity disorder (ADHD) has a substantial genetic component. Yet, due to the complexity of the ADHD phenotype, questions remain as to the specific genes that contribute to this condition as well as the pathways from genes to behavior. Endophenotypes, or phenotypes that are more closely linked to the neurobiological...
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