Article
Relationship between age, molecular markers, and response to sulphadoxine-pyrimethamine treatment in Kampala, Uganda.
Tropical medicine & international health : TM & IH - 1 May 2004
Staedke Sarah G, Sendagire Hakim, Lamola Steven, Kamya Moses R, Dorsey Grant, Rosenthal Philip J
Abstract excerpt
Sulphadoxine/pyrimethamine (SP) has become the first-line treatment of uncomplicated malaria in a number of African countries. Molecular surveillance of resistance-mediating mutations in Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) has been proposed as a means of predicting SP treatment outcomes, but optimal methods of surveillance in different populations have not been...
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